Original Article

The change of heart rate recovery index and Tpeak-end interval values according to age range in healthy men and women

Ayhan Cosgun1, Huseyin Oren2

1Department of Cardiology, Dr. Nafiz Korez Sincan State Hospital, Ankara, Turkey
2Department of Cardiology, Ankara City Hospital, Ankara, Turkey


Background: As age progresses, vagal activity decreases and sympathetic activity increases in both men and women. The purpose of the current study was to examine variations in the Tpeak-end interval and heart rate recovery index (HRR-i) values according to age range in men and women.
Methods: A total of 1481 subjects, including 758 males and 723 females, was included in the study. The study was conducted between March 2013 and January 2020. The effort test was performed and a retrospective study was performed on patient records that were interpreted as negative. The Tpeak-end (Tp-e), QT, corrected QT (QTc), Tp-e/QT, and Tp-e/QTc values were calculated on basal ECGs in the exertion test records. The 1st, 2nd, and 3rd-min HRR-i data were calculated by subtracting the 1st, 2nd, and 3rd-min HR from the peak HR, and then compared.
Results: The Tp-e, QT, QTc values increased as the age range increased in both groups, while the HRR-i data decreased as the age range increased. Values between 70 and 79 years of age appeared similar. It was found that there was a significant negative correlation between the Tp-e interval and the 1st-min HRR-i values.
Conclusions: As the age range increased, the HRR-i values decreased and the Tp-e interval increased.

Keywords: aging; electrocardiography; exercise; heart rate