A case report on pemphigus vulgaris
Sarala V, Sunilkumar S, Keerthana M, Ramu N, Dharani G, Padmavathi B, Bhargavi B, Saikavya N, Srivani M, Saiharshini S
Santhiram College of Pharmacy Nandyal, Kurnool District, AP, India
Pemphigus vulgaris is a rare, chronic autoimmune disease, which is characterized by the overproduction of autoantibodies. These antibodies damage the adhesion of protein (desmoglein) which leads to acantholysis. The primary manifestation is the formation of lesions that get ruptured due to ulcers and form erosions on the skin and mucous membrane. In this case, the patient had developed erosions and ulcers over the scalp, neck, face, and trunk. The possible study efforts were made to prevent the erosions on the skin surface by treating the patient with antibiotics, systemic corticosteroids, immunosuppressive agents, topical creams, and other vital supplements. If the lesions are left untreated, they lead to life-threatening conditions.
Keywords: desmoglein; erosion; hypopigmentation; lesions