Original Article

The most common causes of bacteremia and determination of antibiotic sensitivity pattern


Jamshid Ayatollahi1, Seyed Alireza Mousavi1, Abbas Hajighasemi2, Seyed Hossein Shahcheraghi11

1Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2Medical Student, Shahid Sadoughi University of Medical Sciences, Yazd, Iran


Abstract


Background: Bacteremia refers to the presence of bacteria in the blood. Blood is naturally a sterile environment, so finding bacteria in the blood is always abnormal. Given the growing resistance to nosocomial infections, the identification of dominant pathogens and antibiotic susceptibility patterns in common pathogenic bacteria can be important in empirical and specific therapies against a particular pathogen.
Methods: : In this study, all blood cultures from the beginning to the end of 2018 in Shahid Sadoughi hospital of Yazd were examined in the census. A questionnaire was used to collect demographic and background information. For all positive culture samples, antibiogram data were collected. Studies were conducted on gender, age, hospitalization and underlying disease.
Results: 53.5% of bacteremia was in males and 46.5% in females which had no significant difference. The most common bacteremiacausing organisms were Escherichia coli (17.8%), Staphylococcus aureus (16.9%), Staphylococcus epidermidis (13.9%), and Klebsiella spp. (10.9%).
Conclusions: In the case of hospitalized wards, the overall antibiotic sensitivity was highest in the pediatric ward (70.7%) and lowest in the ICU (34.3%). Diabetic patients with 43.5% had the lowest and patients with a history of malignancy (except neutropenia) with 58.3 were most susceptible to antibiotics, respectively.

Keywords: antibiotic resistance; antibiotic sensitivity; bacteremia; Yazd