Case Report

Clinical manifestation and dental management of Noonan Syndrome


Razeem Khalid Alhassoun

Princess Nourah Bint Abdulrahman University, College of Dentistry, Riyadh, Saudi Arabia


Abstract


Noonan syndrome (NS) is an autosomal dominant condition caused by mutations in multiple genes in the RAS-MAP kinase pathway. It is typically characterized by short stature, broader webbed neck, abnormal chest shape, congenital heart defects, and developmental delay. Oral manifestations include high arched palate, micrognathia, malocclusion, impacted teeth, and giant cells in the jaws. The present report aims at presenting the cranio-dento-facial findings in a case of Noonan syndrome in a 26-year-old female, which was first diagnosed in a dental clinic.

Keywords: craniofacial abnormalities, Noonan syndrome, orofaciodigital