Year: 2019 Vol: 1 Issue: 4


  • International Medicine
  • Worldwide Medicine
  • International Medicine

Review Article

Primary sclerosing cholangitis associated with inflammatory bowel disease

Isaura de Oliveira Carrijo, Leila Aidar Ugrinovich, PatrĂ­cia Ucelli Simioni
Department of Biomedical Science, Faculty of Americana, Americana, SP, Brazil

International Medicine 2019; 1(4): 220-224 | DOI: 10.5455/im.48059      PDF


Abstract


Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by inflammation of the intra and extrahepatic bile ducts with progression to cirrhosis. To the present, the etiology of PSC is not known. Although it is possible to establish a correlation with a genetic predisposition, it is an autoimmune disease, associated with ulcerative colitis and Crohn's disease. There is no proven medical treatment that prolongs survival in PSC, being liver transplantation the only curative treatment, with recurrence of 20% of cases within the first five years after transplantation.

Keywords: autoimmunity, inflammatory bowel disease, primary sclerosing cholangitis, transplantation

International Medicine

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     eISSN         2667-7008

International Medicine
International Medicine
International Medicine
International Medicine
International Medicine
International Medicine
International Medicine
International Medicine
International Medicine
International Medicine