Subdural hematoma with extramedullary hematopoiesisRichard A. Prayson
Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA
International Medicine 2020; 2(1): 85-88 | DOI: 10.5455/im.58240 PDF
Subdural bleeding is commonly associated with trauma and is often associated with tearing of bridging veins. In rare cases, evidence of extramedullary hematopoiesis has been described in association with a subdural hematoma. This paper reports a case of a 77- year-old male with a history of metastatic prostate cancer, hypertension, anemia and type 2 diabetes who presented to the emergency room with a persistent headache and inability to maintain his balance. A computed tomographic (CT) study showed evidence of bilateral hemispheric subacute and chronic subdural hematomas. Surgical evacuation of a lesion on the right and left side of the brain was performed. Examination of histologic sections showed evidence of an organizing subdural hematoma along with erythroid and megakaryocytic precursor cells, consistent with extramedullary hematopoiesis. The literature on this phenomenon will be briefly reviewed.
Keywords: brain, extramedullary hematopoiesis, hemorrhage, subdural hematoma